Bioprinted Skin Recapitulates Normal Collagen Remodeling in Full-Thickness Wounds
نویسندگان
چکیده
منابع مشابه
Topical Simvastatin Enhances Tissue Regeneration in Full-thickness Skin Wounds in Rat Models
Wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. Simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. In this study we aimed to determine the effect of simvastatin on wound healing process in...
متن کاملTissue response to bovine fetal collagen extracellular matrix in full-thickness skin wounds.
OBJECTIVES To present the findings of the biological response and assimilation of bovine fetal collagen (BFC) as observed in biopsy specimens taken after implant. METHODS The biopsy specimens were from 9 patients with full-thickness skin wounds who received the BFC biomaterial in the first stage of a 2-stage reconstruction. Biopsy specimens were taken at the second stage of skin grafting from...
متن کاملTopical Simvastatin Enhances Tissue Regeneration in Full-thickness Skin Wounds in Rat Models
Wounds and wound healing have always been one of the most important subjects that experimental researches were dedicated to. Simvastatin has been used for long as a common lipid lowering agent which was reported to have some pleiotropic effects such as antioxidation, anti-inflammation and immunomodulation. In this study we aimed to determine the effect of simvastatin on wound healing process in...
متن کاملAcceleration of wound healing in acute full-thickness skin wounds using a collagen-binding peptide with an affinity for MSCs
Mesenchymal stem cells (MSCs) have been accepted as a promising cell source in tissue repair and regeneration. However, the inability to enrich MSCs in target areas limits their wide application. As a result, it has been a major goal to induce MSCs to be abundantly and specifically recruited to the injury site. In this study, a peptide with a specific affinity for MSCs (E7 peptide) was immobili...
متن کاملSuppression of α Smooth Muscle Actin Accumulation by Bovine Fetal Dermal Collagen Matrix in Full Thickness Skin Wounds
The suppression of elements associated with wound contracture and unfavorable scarring is a potentially important strategy in clinical wound management. In this study, the presence of α smooth muscle actin (αSMA), a protein involved in wound contraction, was analyzed in a series of wounds in which bovine fetal collagen (BFC) acellular dermal matrix (PriMatrix) was used in staged split thickness...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2020
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2019.0319